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Hepatitis C
HIV/hepatitis C co-infection increases risk of hip fracture

Co-infection with HIV and hepatitis C is associated with an increased risk of hip fracture, US investigators report in Hepatology. Hepatitis C monoinfection also increased the risk

Published
19 June 2012
By
Michael Carter
Bone problems
Treatment Update: Bone Health

Many studies have found that some HIV-positive people tend to have bones that are not as thick or dense as they ought to be. Such bones have reduced bone mineral density, as minerals such as calcium have been removed, rendering the bones more porous and weak.

Published
28 May 2012
From
CATIE
Bone problems
Bisphosphonate Drugs Linked to Atypical Femur Fractures, but Absolute Risk is Small

Use of bisphosphonates, a class of drugs used to manage bone loss and prevent fractures, actually appears to increase the likelihood of an unusual type of femur (thigh bone) fracture, according to a retrospective analysis described in the advance online edition of Archives of Internal Medicine. Researchers emphasized, however, that the absolute risk of atypical femur breaks remains very low.

Published
28 May 2012
From
HIVandHepatitis.com
Bone problems
Zoledronate Protects HIV Positive Men against Bone Loss for at Least 5 Years

The effects of 2 annual doses of zoledronate persist for at least 5 years in HIV positive men on antiretroviral therapy (ART), according to a New Zealand study published in the March 14, 2012, advance online edition of the Journal of Clinical Endocrinology & Metabolism.

Published
11 April 2012
From
HIVandHepatitis.com
Bone problems
CROI: Switching to Tenofovir Increases Bone Turnover, Raltegravir Can Improve Bone Density

HIV positive people who substituted tenofovir (Viread) for zidovudine (AZT; Retrovir) in their antiretroviral regimen showed elevated levels of biomarkers associated with bone turnover and decreased bone mineral density (BMD), researchers reported at the 19th Conference on Retroviruses and Opportunistic Infections (CROI 2012) last month in Seattle.

Published
11 April 2012
From
HIVandHepatitis.com
Bone problems
HIV treatment reduces risk of fractures

Treatment with antiretroviral drugs reduces the risk of low-impact fractures, according to a case-controlled study published in the on-line edition of AIDS. Investigators compared fracture incidence between

Published
14 February 2012
By
Michael Carter
Bone problems
Vitamin D supplements benefit bone metabolism of younger patients taking tenofovir

Vitamin D supplementation is associated with an improvement in a key marker of bone health in HIV-positive young adults treated with tenofovir, US research published in Clinical Infectious

Published
25 January 2012
By
Michael Carter
Bone problems
Vitamin D May Improve Bone Health in Those Taking Anti-HIV Drug

A new NIH-funded study indicates that taking Vitamin D supplements can help prevent hormonal changes that lead to bone loss amongst patients taking tenofovir (Viread) for the long-term treatment of HIV.

Published
12 January 2012
From
National Institutes of Health press release
Side-effects
Limited evidence that vitamin D supplements of any benefit for patients with HIV

There is only scant evidence that vitamin D supplementation is of benefit for patients with HIV, according to UK investigators writing in the January 28th  edition of

Published
10 January 2012
By
Michael Carter
Bone problems
HIV Worsens Bone Loss After Menopause

Compared to a control group, postmenopausal women with HIV infection had higher rates of bone loss and could well have a higher risk for fracture as they age, according to the researchers who conducted the study.

Published
03 January 2012
From
Medscape (requires free registration)
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